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Transgenic Core  
 

TCP Transgenic Core Services

Service Description Details Fees Order
ES Cell Services        
  Gene Targeting using validated ES cell parental lines from the Mount Sinai Hospital Samuel Lunenfeld Research Institute ES cell facility
  Expansion of ES Cell Clones and Their Preparation for the Generation of Chimeras
  Derivation of Novel ES Cell Lines from mutant mice housed at the TCP animal facility
Generation of Chimeras
  • morula aggregation
  • morula/blastocyst microinjection
  • tetraploid complementation assay
Pronuclear Microinjection Transgenic production by pronuclear microinjection of the zygotes
Re-Derivation Re-derivation of mouse strains to Specific Pathogen-Free (SPF) status
Miscellaneous Mouse Services
  • Naturally mated and superovulated timed pregnancy for the dissection of different embryonic stages;
  • Pseudopregnant recipients for embryo transfers;
  • Embryo transfer surgeries.

 

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